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Prucalopride 1–2 mg once daily may be given to patients suffering from chronic constipation for whom laxatives do not provide adequate relief of their symptoms. Patients with severe constipation and slow transit, who frequently develop tolerance to stimulant laxatives, are also eligible for prucalopride treatment
Pantoprazole is used to treat gastroesophageal reflux disease (GERD), a condition that causes gastric juices to flow upward from your stomach and into the esophagus. It also treats conditions in which the stomach makes excess acid, such as Zollinger-Ellison syndrome.